Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575717 | 0.89 | MAPK1 (0.67) | MAPK1CASP3KMT2AGRM5RAB9A | |
| SCHEMBL9194960 | 0.88 | MAPK1 (0.53) | MAPK1CASP3KMT2ARAB9AL3MBTL1 | |
| SCHEMBL29342211 | 0.84 | MAPK1 (0.51) | MAPK1CASP3KMT2AGRM5RAB9A | |
| SCHEMBL23144183 | 0.81 | MAPK1 (0.67) | MAPK1CASP3KMT2AGRM5RAB9A | |
| SCHEMBL10949349 | 0.77 | MAPK1 (0.57) | MAPK1CASP3KMT2AGRM5TDP1 | |
| SCHEMBL9575753 | 0.75 | TSHR (0.52) | MAPK1KMT2A | |
| SCHEMBL8935885 | 0.75 | MAPK1 (0.58) | MAPK1CASP3KMT2ARAB9ATDP1 | |
| SCHEMBL8935936 | 0.74 | MAPK1 (1.00) | MAPK1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL8935897 | 0.74 | MAPK1 (0.70) | MAPK1CASP3KMT2ARAB9ATDP1 | |
| SCHEMBL34464933 | 0.74 | MAPK1 (0.55) | MAPK1CASP3KMT2AGRM5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |