Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935817 | 0.83 | CASP3 (0.48) | MAPK1CASP3RAB9AMMP2MMP9 | |
| SCHEMBL23144183 | 0.80 | MAPK1 (0.67) | MAPK1CASP3RAB9AKMT2ATDP1 | |
| SCHEMBL9575717 | 0.80 | MAPK1 (0.67) | MAPK1CASP3RAB9AKMT2ATDP1 | |
| SCHEMBL9575755 | 0.75 | MAPK1 (0.59) | MAPK1CASP3RAB9AKMT2ATDP1 | |
| SCHEMBL8935936 | 0.74 | MAPK1 (1.00) | MAPK1RAB9ACA1KMT2ALMNA | |
| SCHEMBL8935897 | 0.74 | MAPK1 (0.70) | MAPK1CASP3RAB9AKMT2ATDP1 | |
| SCHEMBL29811681 | 0.74 | MAPK1 (1.00) | MAPK1RAB9ACA1KMT2ALMNA | |
| SCHEMBL9675693 | 0.72 | CA1 (0.43) | MAPK1CA1TDP1 | |
| SCHEMBL10052099 | 0.71 | MAPK1 (0.65) | MAPK1CASP3RAB9AKMT2ATDP1 | |
| SCHEMBL30445427 | 0.70 | MAPK1 (0.53) | MAPK1CASP3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5531978-A | CHELATE COMPOUNDS, IMAGING | NYCOMED IMAGING AS (NO) | 1996-07-02 | — | — | US | disclosed |
| US-5419893-A | Aminopolycarboxylic acids and derivatives thereof for magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1995-05-30 | — | — | US | disclosed |
| US-5198208-A | Chelate compounds for diagnosis by magnetic resonance imaging, ultrasound or radiation therapy | NYCOMED IMAGING AS (NO) | 1993-03-30 | — | — | US | disclosed |
| EP-0466200-A1 | Aminocarboxylic acids and derivatives thereof | NYCOMED IMAGING AS (NO) | 1992-01-15 | — | — | EP | disclosed |
| WO-1989000557-A1 | AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1989-01-26 | — | — | WO | disclosed |