Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.59 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709219 | 0.89 | MAPT (0.69) | PDE7APDE7BMAPTLMNAMEN1 | |
| SCHEMBL9575567 | 0.80 | HPGD (0.55) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL6743647 | 0.78 | PDE7A (0.73) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL9669403 | 0.77 | PDE7A (0.56) | PDE7APDE7BMAPTLMNAMEN1 | |
| SCHEMBL19048971 | 0.77 | PDE7A (0.71) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL30338244 | 0.77 | PDE7A (0.65) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL1713219 | 0.77 | PDE7A (0.65) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL6039967 | 0.76 | TXNRD1 (0.74) | PDE7APDE7BMAPTLMNAMEN1 | |
| SCHEMBL11253450 | 0.75 | MAPT (0.59) | PDE7APDE7BMAPTLMNAMEN1 | |
| SCHEMBL2968510 | 0.75 | PDE7A (0.68) | PDE7APDE7BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |