Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950770 | 1.00 | HCAR2 (0.57) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL27660385 | 1.00 | HCAR2 (0.57) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL950768 | 0.91 | TSHR (0.43) | HCAR2TSHRATMKEAP1NFE2L2 | |
| SCHEMBL301454 | 0.91 | TSHR (0.43) | HCAR2TSHRATMKEAP1NFE2L2 | |
| SCHEMBL301455 | 0.91 | TSHR (0.43) | HCAR2TSHRATMKEAP1NFE2L2 | |
| Acetic Acid Methyl Ester SCHEMBL20483629 | 0.91 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL28398903 | 0.86 | HCAR2 (0.42) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL2774698 | 0.86 | HCAR2 (0.42) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL29185573 | 0.85 | HCAR2 (0.47) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL11654063 | 0.84 | HCAR2 (0.53) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668951-B2 | Pharmaceutical compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2017-06-06 | — | — | US | claimed |
| US-9375390-B2 | Agricultural compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2016-06-28 | — | — | US | claimed |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-8598231-B2 | Flavoring agents containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2013-12-03 | — | — | US | claimed |
| US-20130210934-A1 | FLAVORING AGENTS CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | DuPont Run & Lyle Bio Products Company, LLC (US) | 2013-08-15 | — | — | US | claimed |
| US-8436046-B2 | Detergent composition containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2013-05-07 | — | — | US | claimed |
| US-8309116-B2 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2012-11-13 | — | — | US | claimed |
| US-20120071390-A1 | DETERGENT COMPOSITION CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2012-03-22 | — | — | US | claimed |
| US-8048920-B2 | Personal care composition containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2011-11-01 | — | — | US | claimed |
| EP-1991515-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS FOR BIOMASS-DERIVED EXTRACTS FRAGRANCE CONCENTRATES, AND OILS | DuPont Tate & Lyle Bio Products Company, LLC (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2008123845-A2 | COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2008-10-16 | — | — | WO | claimed |
| US-20070213247-A1 | Detergent and liquid soap compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-13 | — | — | US | claimed |
| US-20070207939-A1 | Compositions comprising mono and di esters of biologically-based 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-06 | — | — | US | claimed |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE &LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203276-A1 | Plasticizers comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203323-A1 | Food compositions comprising biologically-based biodegradable 1,3-propanediol esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| WO-2007095262-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2007-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071390-A1 | DETERGENT COMPOSITION CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | PHOSPHO1, ABHD11, DEGS1 | HCAR2 1390/4885TSHR 4379/4885TP53 2655/4885 |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | DECR1, DECR2, HSD17B12 | HCAR2 519/4885TSHR 4727/4885TP53 3246/4885 |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BMP2, PGD, EBP | HCAR2 1339/4885TSHR 4738/4885TP53 2771/4885 |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, CYP3A43 | HCAR2 399/4885TSHR 4172/4885TP53 754/4885 |
| US-20130210934-A1 | FLAVORING AGENTS CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | ALDH1A3, ALDH1A1, ALDH18A1 | HCAR2 592/4885TSHR 3931/4885TP53 1356/4885 |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, HPD | HCAR2 860/4885TSHR 4644/4885TP53 1257/4885 |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | PBDC1, CUTA, EBP | HCAR2 407/4885TSHR 3598/4885TP53 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.