Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577182 | 0.90 | POLB (0.50) | POLBATMGAAALDH1A1KMT2A | |
| SCHEMBL9577232 | 0.78 | GAA (0.69) | POLBGAAALDH1A1GSTO1HSD17B10 | |
| SCHEMBL6851806 | 0.77 | ATM (0.47) | POLBATMGAAGUSBALDH1A1 | |
| SCHEMBL2371939 | 0.76 | KMT2A (0.46) | POLBATMGUSBGSTO1PGR | |
| SCHEMBL12190304 | 0.76 | GUSB (0.46) | POLBATMGUSBPGRCDK1 | |
| SCHEMBL2371936 | 0.76 | GUSB (0.46) | POLBATMGUSBPGRCDK1 | |
| SCHEMBL8530768 | 0.76 | GUSB (0.46) | POLBATMGUSBPGRCDK1 | |
| SCHEMBL9771059 | 0.75 | ALDH1A1 (0.42) | POLBATMGAAGUSBALDH1A1 | |
| SCHEMBL11689501 | 0.75 | L3MBTL1 (0.48) | POLBATMGAAALDH1A1KMT2A | |
| SCHEMBL11689629 | 0.75 | GSTO1 (0.51) | POLBATMGAAALDH1A1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4957958-A | IMPROVED MELT FLOW | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |