Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455145 | 1.00 | RECQL (0.55) | RECQLPPARACA2CA1HTT | |
| SCHEMBL10455301 | 1.00 | RECQL (0.55) | RECQLPPARACA2CA1HTT | |
| SCHEMBL9577199 | 1.00 | RECQL (0.55) | RECQLPPARACA2CA1HTT | |
| SCHEMBL9577170 | 0.84 | CA1 (0.46) | RECQLPPARACA2CA1ALDH1A1 | |
| SCHEMBL10455176 | 0.77 | RECQL (0.62) | RECQLPPARACA2CA1HTT | |
| SCHEMBL9577187 | 0.77 | RECQL (0.62) | RECQLPPARACA2CA1HTT | |
| SCHEMBL9577172 | 0.77 | RECQL (0.62) | RECQLPPARACA2CA1HTT | |
| SCHEMBL9577248 | 0.77 | RECQL (0.62) | RECQLPPARACA2CA1HTT | |
| SCHEMBL198440 | 0.74 | ALDH1A1 (0.56) | RECQLPPARAHTTMEN1TSHR | |
| SCHEMBL4747454 | 0.74 | FABP4 (0.66) | RECQLPPARACA2CA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |