Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577218 | 0.84 | RECQL (0.55) | CA1CA12CA9CA2PPARA | |
| SCHEMBL10455145 | 0.84 | RECQL (0.55) | CA1CA12CA9CA2PPARA | |
| SCHEMBL9577199 | 0.84 | RECQL (0.55) | CA1CA12CA9CA2PPARA | |
| SCHEMBL10455301 | 0.84 | RECQL (0.55) | CA1CA12CA9CA2PPARA | |
| SCHEMBL10455161 | 0.82 | ALDH1A1 (0.42) | CA1CA9CA2SIGMAR1ALDH1A1 | |
| SCHEMBL10455208 | 0.74 | RECQL (0.45) | CA1CA12CA9CA2RECQL | |
| SCHEMBL9577125 | 0.70 | RECQL (0.49) | CA1CA12CA9CA2RECQL | |
| SCHEMBL3687291 | 0.69 | L3MBTL1 (0.61) | CA1CA2POLBL3MBTL1FABP4 | |
| SCHEMBL3019231 | 0.69 | SIGMAR1 (0.70) | CA1CA12CA9CA2SIGMAR1 | |
| SCHEMBL9577130 | 0.69 | SMN1; SMN2 (0.36) | CA1CA12CA9CA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |