Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21561158 | 0.86 | CYP2C19 (0.71) | CYP2C19FFAR2KMT2AATML3MBTL1 | |
| SCHEMBL19803299 | 0.86 | CYP2C19 (0.71) | CYP2C19FFAR2KMT2AATML3MBTL1 | |
| SCHEMBL4029220 | 0.86 | CYP2C19 (0.71) | CYP2C19FFAR2KMT2AATML3MBTL1 | |
| SCHEMBL9577255 | 0.84 | CYP2C19 (0.73) | CYP2C19L3MBTL1CYP2D6LMNATSHR | |
| SCHEMBL13946462 | 0.83 | FFAR2 (0.52) | CYP2C19FFAR2KMT2AATML3MBTL1 | |
| SCHEMBL19803300 | 0.81 | FFAR2 (0.51) | CYP2C19FFAR2KMT2AATML3MBTL1 | |
| SCHEMBL9577376 | 0.80 | CYP2C19 (0.49) | CYP2C19L3MBTL1CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL1289928 | 0.77 | CYP2C9 (0.48) | CYP2C19FFAR2KMT2AL3MBTL1POLB | |
| SCHEMBL9577362 | 0.76 | CYP2C9 (0.47) | CYP2C19KMT2APOLBCYP2C9MEN1 | |
| SCHEMBL9577449 | 0.75 | FFAR2 (0.49) | CYP2C19FFAR2KMT2APOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |