Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445129 | 0.88 | CYP2C19 (0.65) | CYP2C19FFAR1PKML3MBTL1LDHA | |
| SCHEMBL28493071 | 0.87 | CYP2C19 (0.47) | CYP2C19FFAR1PKMKDM4EL3MBTL1 | |
| SCHEMBL28501622 | 0.87 | CYP2C19 (0.47) | CYP2C19FFAR1PKMKDM4EL3MBTL1 | |
| SCHEMBL8656436 | 0.86 | PKM (0.50) | CYP2C19FFAR1PKML3MBTL1LDHA | |
| SCHEMBL7270733 | 0.82 | LMNA (0.50) | CYP2C19PKMNPC1MAPTRAB9A | |
| SCHEMBL28606284 | 0.81 | SMN1; SMN2 (0.53) | CYP2C19PKML3MBTL1NPC1MAPT | |
| SCHEMBL9577255 | 0.80 | CYP2C19 (0.73) | CYP2C19KDM4EL3MBTL1MAPTNPSR1 | |
| SCHEMBL9577302 | 0.80 | CYP2C19 (0.53) | CYP2C19L3MBTL1TSHRCYP3A4CYP1A2 | |
| Acetic Acid SCHEMBL28193316 | 0.77 | AOC3 (0.47) | CYP2C19FFAR1PKMKDM4EL3MBTL1 | |
| SCHEMBL28496900 | 0.76 | ALOX15 (0.41) | CYP2C19FFAR1PKMKDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |