Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577449 | 0.86 | FFAR2 (0.49) | CYP2C9CYP2C19POLBFFAR2KMT2A | |
| SCHEMBL16075922 | 0.85 | POLB (0.58) | CYP2C9CYP2C19POLBFFAR2KMT2A | |
| SCHEMBL1742115 | 0.85 | POLB (0.58) | CYP2C9CYP2C19POLBFFAR2KMT2A | |
| SCHEMBL7711076 | 0.85 | POLB (0.58) | CYP2C9CYP2C19POLBFFAR2KMT2A | |
| SCHEMBL9872058 | 0.83 | ALDH1A1 (0.53) | CYP2C9CYP2C19POLBKMT2AMEN1 | |
| SCHEMBL710418 | 0.82 | LMNA (0.56) | POLBKMT2AMEN1KCNQ2CRHBP | |
| SCHEMBL10443324 | 0.81 | KCNQ2 (0.43) | KMT2AMEN1KCNQ2CRHBPCRHR2 | |
| SCHEMBL10443280 | 0.81 | KMT2A (0.43) | KMT2AMEN1CRHBPCRHR2LMNA | |
| SCHEMBL10443246 | 0.81 | CRHBP (0.54) | CYP2C9CYP2C19POLBKMT2AMEN1 | |
| SCHEMBL9588276 | 0.81 | FFAR2 (0.49) | CYP2C9CYP2C19POLBFFAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386243-A1 | PLATINUM (II) COMPLEXES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-09-12 | — | — | EP | disclosed |