Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997295 | 0.88 | SRC (0.42) | TDP1MAPTMEN1KMT2AHIF1A | |
| SCHEMBL991240 | 0.79 | SRC (0.50) | TDP1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL74366 | 0.78 | SRC (0.56) | TDP1CYP2D6SRCCYP2C19 | |
| SCHEMBL9835478 | 0.77 | CYP2C9 (0.46) | POLBMEN1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL7402774 | 0.77 | ALDH1A1 (0.44) | POLBSMN1; SMN2CNR2CNR1MAPT | |
| SCHEMBL28474964 | 0.77 | LDHA (0.45) | SMN1; SMN2CNR2CNR1MEN1KMT2A | |
| SCHEMBL11259540 | 0.77 | HDAC3 (0.45) | SMN1; SMN2CNR2ALDH1A1 | |
| SCHEMBL7823663 | 0.77 | ALDH1A1 (0.44) | POLBSMN1; SMN2CNR2CNR1MAPT | |
| SCHEMBL11155958 | 0.76 | SRC (0.61) | TDP1POLBSMN1; SMN2GRM8GRM7 | |
| Hydrochloric Acid SCHEMBL8340022 | 0.76 | SRC (0.54) | TDP1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237074-A | Diels-alder reaction using maleic anhydride | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |
| US-4283542-A | BY REACTING PHOSPHATE ESTER WITH AN AMINE TO PRODUCE AN AMPHOTERIC SURFACTANT | MONA INDUSTRIES (US) | 1981-08-11 | — | — | US | disclosed |