Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6636145 | 1.00 | — | — | |
| Propane SCHEMBL9765341 | 0.87 | ALOX15 (0.46) | ALDH1A1ALOX15LMNABLMPMP22 | |
| Urea SCHEMBL1064520 | 0.87 | — | — | |
| Acetamide SCHEMBL115226 | 0.83 | — | — | |
| Acetamide SCHEMBL17847056 | 0.83 | LMNA (0.67) | ALDH1A1TSHRALOX15LMNABLM | |
| Carbamic Acid SCHEMBL8333796 | 0.83 | — | — | |
| Carbamic Acid SCHEMBL11744787 | 0.83 | ACHE (0.58) | ALDH1A1TSHRALOX15LMNABLM | |
| Urea SCHEMBL8740637 | 0.83 | — | — | |
| Urea SCHEMBL6723116 | 0.83 | — | — | |
| Urea SCHEMBL11150246 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331554-B1 | COMPOSITION, WHICH PERMITS TO MAKE COMPATIBLE AT LEAST TWO INCOMPATIBLE THERMOPLASTIC POLYMERS, ITS APPLICATION FOR THE FABRICATION OF THERMOPLASTIC ALLOYS AND THERMOPLASTIC ALLOYS OBTAINED | ELF ATOCHEM S.A. (FR) | 1993-07-28 | — | — | EP | disclosed |
| EP-0331554-A1 | Composition, which permits to make compatible at least two incompatible thermoplastic polymers, its application for the fabrication of thermoplastic alloys and thermoplastic alloys obtained | ELF ATOCHEM S.A. (FR) | 1989-09-06 | — | — | EP | disclosed |