SCHEMBL9577463

SCHEMBL9577463

CC(C)=C1OC(=O)N(c2cc(OC(C)C)c(Cl)cc2F)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 8/20 0.47
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KMO O15229 2/20 0.34
RORC P51449 1/20 0.34
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX12 P18054 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835969 0.89 PPOX (0.45) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9619952 0.89 PPOX (0.44) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL8886715 0.89 PPOX (0.44) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL7592035 0.88 PPOX (0.39) PPOX
SCHEMBL9577486 0.87 PPOX (0.51) PPOXKMT2AMAPTNPSR1KDM4E
SCHEMBL9775325 0.85 PPOX (0.61) PPOXGAAMAPTNPSR1KDM4E
SCHEMBL9620060 0.85 CUL4A (0.43) PPOXMAPTHTTNPSR1ALDH1A1
SCHEMBL9577505 0.81 PPOX (0.42) PPOXGAAKDM4EALDH1A1HPGD
SCHEMBL7932830 0.80 PPOX (0.32) PPOXMEN1KMT2AGAACYP1A2
SCHEMBL9577438 0.80 PPOX (0.50) PPOXGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350880-B1 HERBICIDAL COMPOSITION AND HERBICIDAL METHOD Kaken Pharmaceutical Co., Ltd. (JP) 1993-04-07 EP claimed
EP-0350880-A2 Herbicidal composition and herbicidal method Kaken Pharmaceutical Co., Ltd. (JP) 1990-01-17 EP claimed
EP-0350880-B1 HERBICIDAL COMPOSITION AND HERBICIDAL METHOD Kaken Pharmaceutical Co., Ltd. (JP) 1993-04-07 EP disclosed
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-5024692-A Oxazolidinedione and phosphorus containing amino acid mixture KAKEN PHARMACEUTICAL CO., LTD. (JP) 1991-06-18 US disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed
EP-0350880-A2 Herbicidal composition and herbicidal method Kaken Pharmaceutical Co., Ltd. (JP) 1990-01-17 EP disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed