SCHEMBL9619952

SCHEMBL9619952

CCC(C)=C1OC(=O)N(c2cc(OC(C)C)c(Cl)cc2F)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 9/20 0.44
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NR1I2 O75469 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KMO O15229 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GAA P10253 1/20 0.32
RORC P51449 1/20 0.32
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577463 0.89 PPOX (0.47) PPOXMEN1KMT2ANR1I2TDP1
SCHEMBL9577518 0.82 PPOX (0.38) PPOXLMNA
SCHEMBL8886715 0.81 PPOX (0.44) PPOXMEN1KMT2ANR1I2TDP1
SCHEMBL9775325 0.80 PPOX (0.61) PPOXMAPTNPSR1GAAKDM4E
SCHEMBL9835969 0.78 PPOX (0.45) PPOXMEN1KMT2ANR1I2TDP1
SCHEMBL9577667 0.78 PPOX (0.48) PPOXMEN1KMT2ANR1I2TDP1
SCHEMBL9619954 0.78 PPOX (0.44) PPOXMEN1KMT2ANR1I2TDP1
SCHEMBL7592035 0.78 PPOX (0.39) PPOX
SCHEMBL9577486 0.76 PPOX (0.51) PPOXKMT2AMAPTNPSR1LMNA
SCHEMBL9620060 0.75 CUL4A (0.43) PPOXMAPTHTTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed