SCHEMBL9577438

SCHEMBL9577438

C=CCOc1cc(N2C(=O)OC(=C(C)C)C2=O)c(F)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPOX P50336 14/20 0.50
HTR2C P28335 2/20 0.34
HTR2B P41595 2/20 0.34
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577505 0.86 PPOX (0.42) PPOXGAA
SCHEMBL9577486 0.83 PPOX (0.51) PPOXTSHR
SCHEMBL9577496 0.83 PPOX (0.38) PPOX
SCHEMBL9577463 0.80 PPOX (0.47) PPOXGAATSHR
SCHEMBL9620060 0.79 CUL4A (0.43) PPOX
SCHEMBL9655385 0.79 PPOX (0.52) PPOXHTR2CHTR2BGAA
SCHEMBL7936557 0.79 ALDH1A1 (0.38) PPOX
SCHEMBL9775325 0.78 PPOX (0.61) PPOXGAATSHR
SCHEMBL7932830 0.77 PPOX (0.32) PPOXGAA
Pentoxazone SCHEMBL38904 0.77 PPOX (0.51) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350880-B1 HERBICIDAL COMPOSITION AND HERBICIDAL METHOD Kaken Pharmaceutical Co., Ltd. (JP) 1993-04-07 EP claimed
EP-0350880-A2 Herbicidal composition and herbicidal method Kaken Pharmaceutical Co., Ltd. (JP) 1990-01-17 EP claimed
EP-0350880-B1 HERBICIDAL COMPOSITION AND HERBICIDAL METHOD Kaken Pharmaceutical Co., Ltd. (JP) 1993-04-07 EP disclosed
US-5024692-A Oxazolidinedione and phosphorus containing amino acid mixture KAKEN PHARMACEUTICAL CO., LTD. (JP) 1991-06-18 US disclosed
EP-0350880-A2 Herbicidal composition and herbicidal method Kaken Pharmaceutical Co., Ltd. (JP) 1990-01-17 EP disclosed