Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 12/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326269 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TSHRASAH1TLR8CNR2 | |
| SCHEMBL9577554 | 0.83 | ASAH1 (0.63) | ALDH1A1TSHRASAH1CNR2 | |
| SCHEMBL9716174 | 0.79 | TSHR (0.56) | ALDH1A1TSHRASAH1TLR8CNR2 | |
| SCHEMBL28945638 | 0.76 | ASAH1 (0.54) | ALDH1A1TSHRASAH1TLR8 | |
| SCHEMBL29795694 | 0.76 | ASAH1 (0.54) | ALDH1A1TSHRASAH1TLR8 | |
| SCHEMBL28794567 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TSHRASAH1TLR8 | |
| SCHEMBL29795389 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TSHRASAH1TLR8 | |
| SCHEMBL4399571 | 0.71 | ALDH1A1 (0.64) | ALDH1A1TSHRASAH1CNR2 | |
| SCHEMBL11797936 | 0.70 | ALDH1A1 (0.49) | ALDH1A1TSHRASAH1TLR8KDM4E | |
| SCHEMBL9577522 | 0.70 | ASAH1 (0.43) | ALDH1A1TSHRASAH1TLR8CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115917324-A | Methods of treating cancer | 布罗德研究所有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-5264213-A | Benzoyl phenyl ureas | DOWELANCO (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0349999-A2 | Process for preparing highly active water-dispersible pesticides | DOWELANCO (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4840959-A | Pyridinecarboxamide derivatives and their use as fungicide | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4618620-A | BENZIMIDAZOLE-THIOPHANATE TYPES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-10-21 | — | — | US | disclosed |
| US-3978091-A | FUNGICIDES, INSECTICIDES, NEMATOCIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |