Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445279 | 0.74 | MMP8 (0.36) | LMNATSHRALDH1A1GAA | |
| SCHEMBL901650 | 0.72 | — | — | |
| SCHEMBL5746457 | 0.71 | ALDH1A1 (0.35) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL250869 | 0.69 | — | — | |
| SCHEMBL7910108 | 0.69 | HMGCR (0.33) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL289489 | 0.68 | HDAC1 (0.43) | LMNACHRM1ADRA1ATSHRALDH1A1 | |
| SCHEMBL13806868 | 0.67 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL16368775 | 0.67 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL11105202 | 0.67 | TSHR (0.40) | LMNATSHRHIF1AALDH1A1 | |
| SCHEMBL10430794 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376859-B1 | METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | claimed |
| US-5051529-A | Transesterification, amidation and acetoacetylation of amines, alcohols, mercaptans and polymers | EASTMAN KODAK COMPANY (US) | 1991-09-24 | — | — | US | claimed |
| EP-0376859-A1 | Method for functionalization of nucleophiles | EASTMAN KODAK COMPANY (US) | 1990-07-04 | — | — | EP | claimed |