Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589896 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL982446 | 0.82 | GABRA1 (0.47) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL24450927 | 0.82 | GABRA1 (0.40) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL68691 | 0.79 | GABRA1 (0.48) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL11582637 | 0.78 | BID (0.45) | ALDH1A1ATMALOX15HSD17B10MMP2 | |
| SCHEMBL3225381 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL29377115 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL27952990 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL1837261 | 0.77 | TSHR (0.44) | ALDH1A1TDP1TSHRGABRA1GABRB2 | |
| SCHEMBL8679703 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196492-A | Aliphatic polyol reduces coloring, colorless and dyeable, ophthalmic lenses | ENICHEM SYNTHESIS S.P.A. (IT) | 1993-03-23 | — | — | US | claimed |