Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 11/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21694265 | 0.80 | USP7 (0.45) | ALDH1A1USP7ABL1ABCB1BCR | |
| SCHEMBL982446 | 0.77 | GABRA1 (0.47) | ALDH1A1TSHRTDP1 | |
| SCHEMBL344517 | 0.76 | ABL1 (0.50) | ALDH1A1TSHRTDP1ABL1ABCB1 | |
| SCHEMBL9577896 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1ESR2ESR1 | |
| SCHEMBL1837261 | 0.73 | TSHR (0.44) | ALDH1A1TSHRTDP1ESR2ESR1 | |
| SCHEMBL584830 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1ESR2ESR1 | |
| SCHEMBL29613273 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1ESR2ESR1 | |
| SCHEMBL7942890 | 0.72 | ABL1 (0.41) | ALDH1A1TSHRUSP7ABL1ABCB1 | |
| SCHEMBL2683682 | 0.71 | ALDH1A1 (0.56) | ALDH1A1USP7ESR2ESR1HPGD | |
| SCHEMBL985288 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739257-A | INTERFACIAL POLYMERIZATION OF A DIHYDROXY COMPOUND AND PHOSGENE IN THE PRESENCE OF METHYLTRIBUTYLAMMONIUM HALIDE OR HEXABUTYLBUTYLENEDIAMMONIUM HALIDE | GENERAL ELECTRIC COMPANY (US) | 1998-04-14 | — | — | US | disclosed |