SCHEMBL9579281

SCHEMBL9579281

O=C1CC(c2ccccc2)c2cccc(O)c21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.60
KDM4E B2RXH2 1/20 0.44
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP1B1 Q16678 1/20 0.41
PLK1 P53350 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074584 0.80 EEF2K (0.60) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL181713 0.74 KDM4E (0.56) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL8873657 0.74 KDM4E (0.56) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL29657292 0.74 KDM4E (0.56) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL27661112 0.74 STAT3 (0.48) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL8220088 0.73 ALDH1A1 (0.56) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL27721949 0.72 STAT3 (0.43) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL23480266 0.72 CYP19A1 (0.49) KDM4EALDH1A1HSD17B10GAAMEN1
SCHEMBL12162742 0.72 IDO1 (0.42) EEF2KKDM4EALDH1A1HSD17B10GAA
SCHEMBL9329821 0.71 KDM4E (0.59) EEF2KKDM4EALDH1A1HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105934498-A Encoded chromophoric polymer particles 华盛顿大学商业中心 2016-09-07 CN claimed
CN-109913203-A Chromophoric polymers point with narrow emission 华盛顿大学商业中心 2019-06-21 CN disclosed
CN-104487097-B Chromophoric polymer dots with narrow-band emission 华盛顿大学商业中心 2019-01-18 CN disclosed
CN-103087477-B Polymer matrix electroluminescent materials and devices 住友化学株式会社 2017-04-12 CN disclosed
CN-105934498-A Encoded chromophoric polymer particles 华盛顿大学商业中心 2016-09-07 CN disclosed
CN-102516719-B Polymer matrix electroluminescent material and device SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-03-23 CN disclosed
CN-104487097-A Chromophoric polymer dots with narrow-band emission UNIV WASHINGTON CT COMMERCIALIZATION 2015-04-01 CN disclosed
CN-103087477-A Polymer matrix electroluminescent materials and devices SUMITOMO CHEMICAL CO 2013-05-08 CN disclosed
CN-102516720-A Polymer matrix electroluminescent materials and devices SUMITOMO CHEMICAL CO 2012-06-27 CN disclosed
CN-102516719-A Polymer matrix electroluminescent materials and devices SUMITOMO CHEMICAL CO 2012-06-27 CN disclosed
CN-1441826-A Polymer Matrix Electroluminescent Materials and Devices MAXDEN INC (US) 2003-09-10 CN disclosed
US-5242919-A Antiinflammatory agents or hypotensive agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-09-07 US disclosed
US-5055474-A Antihypoxia, hypotensive, antiinflammatory agents; anoxia treatment OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-10-08 US disclosed
EP-0173331-B1 2,3-DIHYDRO-1H-INDENE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-14 EP disclosed
US-4895847-A ANTIHYPOXIC, ANTIINFLAMMATORY, HYPOTENSIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-01-23 US disclosed
US-4788130-A ANTIHYDOXIC, HYPOTENSIVE, ANTIINFLAMMATORY AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-11-29 US disclosed
EP-0173331-A2 2,3-Dihydro-1H-indene derivatives, a process for preparing them and pharmaceutical compositions containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-03-05 EP disclosed