Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15074875 | 0.81 | TET2 (0.43) | TET2HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL13623135 | 0.79 | TET2 (0.32) | TET2GAA | |
| SCHEMBL9015652 | 0.77 | ALDH1A1 (0.37) | GAAHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10883335 | 0.75 | TET2 (0.34) | TET2TSHR | |
| SCHEMBL19400457 | 0.75 | TET2 (0.30) | TET2 | |
| SCHEMBL2178900 | 0.74 | HMGCR (0.52) | GAAHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL11258432 | 0.74 | TDP1 (0.33) | TET2TDP1HSD17B10 | |
| SCHEMBL15188580 | 0.74 | HSD17B10 (0.33) | TET2TDP1HSD17B10 | |
| SCHEMBL22167507 | 0.72 | TDP1 (0.32) | TDP1HSD17B10 | |
| SCHEMBL13544793 | 0.72 | LMNA (0.38) | GAAHMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568367-B1 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2007-04-18 | — | — | EP | disclosed |
| EP-0381964-B1 | PROCESS FOR THE PREPARATION OF POLYUNSATURATED CYCLIC COMPOUNDS | FIRMENICH SA (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-4967033-A | Process for the preparation of polyunsaturated cyclic compounds | FIRMENICH S.A. (CH) | 1990-10-30 | — | — | US | disclosed |
| EP-0381964-A1 | Process for the preparation of polyunsaturated cyclic compounds | FIRMENICH SA (CH) | 1990-08-16 | — | — | EP | disclosed |