Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.52 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.52 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29689457 | 0.89 | CYP2D6 (0.62) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL2155401 | 0.89 | CYP2D6 (0.62) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL7528741 | 0.87 | GRIN2A (0.52) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL6879512 | 0.85 | GPBAR1 (0.55) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL1490581 | 0.85 | GPBAR1 (0.55) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL5790619 | 0.85 | ST6GAL1 (0.50) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL9580263 | 0.84 | OSBP (0.53) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL5667888 | 0.83 | VDR (0.69) | CASP7TP53HSD17B10GPBAR1TDP1 | |
| SCHEMBL7666745 | 0.83 | GPBAR1 (0.50) | OSBPOSBP2ST6GAL1CYP2C19GRIN2A | |
| SCHEMBL5154450 | 0.83 | VDR (0.69) | CASP7TP53HSD17B10GPBAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |