Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615812 | 0.92 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL9278177 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL8649755 | 0.90 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL4966118 | 0.83 | XDH (0.52) | SMN1; SMN2MAPTMEN1KMT2AXDH | |
| SCHEMBL9245694 | 0.83 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL1491731 | 0.81 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL10586609 | 0.81 | CYP11B1 (0.48) | KDM1AALDH1A1KDM4EHPGDGABRA1 | |
| SCHEMBL10340731 | 0.80 | CYP11B1 (0.51) | SMN1; SMN2NPC1RAB9AMAPTHSD17B1 | |
| SCHEMBL10587436 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 | |
| SCHEMBL9282898 | 0.78 | XDH (0.41) | SMN1; SMN2NPC1RAB9AMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5320140-A | — | — | None | — | — | JP | disclosed |
| JP-H05320140-A | NEW ESTER COMPOUND, LIQUID CRYSTAL COMPOSITION AND OPTICAL SWITCHING ELEMENT | JAPAN ENERGY CORP | 1993-12-03 | — | — | JP | disclosed |