Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615812 | 0.98 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9580386 | 0.90 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9278177 | 0.90 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9326066 | 0.83 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL4948816 | 0.82 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9604754 | 0.81 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL10748009 | 0.80 | CASP3 (0.63) | RAB9ASMN1; SMN2NPC1MAPTTP53 | |
| SCHEMBL9637460 | 0.80 | CYP11B1 (0.53) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL7159704 | 0.79 | MEN1 (0.55) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL10752849 | 0.79 | CYP11B1 (0.56) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4290871-A | — | — | None | — | — | JP | disclosed |
| JP-5239027-A | — | — | None | — | — | JP | disclosed |
| JP-63165370-A | — | — | None | — | — | JP | disclosed |
| EP-0518189-B1 | Phenyl pyridins | ROLIC AG (CH) | 1998-07-08 | — | — | EP | disclosed |
| US-5371230-A | Phenylpyridine derivatives and liquid crystalline mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1994-12-06 | — | — | US | disclosed |
| JP-H05239027-A | PHENYLPYRIDINE DERIVATIVE | F HOFFMANN LA ROCHE AG | 1993-09-17 | — | — | JP | disclosed |
| EP-0518189-A2 | Phenyl pyridins | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-16 | — | — | EP | disclosed |
| JP-H04290871-A | PYRIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND TIME-SHARED LIQUID CRYSTAL DISPLAY PRODUCED BY USING THE COMPOSITION | SEIKO EPSON CORP | 1992-10-15 | — | — | JP | disclosed |
| JP-S63165370-A | PYRIMIDINE COMPOUND | ADEKA ARGUS CHEM CO LTD | 1988-07-08 | — | — | JP | disclosed |
| US-4752413-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-06-21 | — | — | US | disclosed |
| EP-0247804-A2 | 2-(Alkyloxycarbonyloxyphenyl)-5-alkylpyridine and composition containing same | Chisso Corporation (JP) | 1987-12-02 | — | — | EP | disclosed |