Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967653 | 0.76 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3NPSR1CYP2D6 | |
| SCHEMBL21586875 | 0.75 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3BACE1NPSR1 | |
| SCHEMBL21728894 | 0.74 | CYP3A4 (0.43) | SLC6A2SLC6A4SLC6A3BACE1TAAR1 | |
| SCHEMBL9839154 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3BACE1NPSR1 | |
| SCHEMBL3829782 | 0.71 | SLC6A3 (0.41) | SLC6A2SLC6A4SLC6A3BACE1NPSR1 | |
| SCHEMBL9430556 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3BACE1NPSR1 | |
| SCHEMBL28190200 | 0.69 | NPSR1 (0.43) | SLC6A2SLC6A4SLC6A3BACE1NPSR1 | |
| SCHEMBL13983003 | 0.69 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8461900 | 0.68 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3NPSR1 | |
| SCHEMBL21610833 | 0.68 | HPGD (0.43) | NPSR1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |