Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460862 | 0.86 | KMO (0.43) | TSHRSRD5A2PDE5ASLC6A4SLC6A3 | |
| SCHEMBL8036360 | 0.85 | ALOX15 (0.50) | TSHRSRD5A2PDE5ACCR2RXRA | |
| SCHEMBL8034546 | 0.81 | RXRA (0.36) | TSHREPHX2RARBRARGRXRA | |
| SCHEMBL8780006 | 0.80 | NAMPT (0.38) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL8036369 | 0.80 | MAOB (0.42) | TSHRSRD5A2 | |
| Hydrochloric Acid SCHEMBL8038381 | 0.79 | MAOB (0.43) | TSHRSRD5A2 | |
| SCHEMBL8057747 | 0.78 | LMNA (0.49) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8054861 | 0.76 | SLC16A3 (0.42) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8055091 | 0.74 | TSHR (0.46) | TSHRSLC6A4SLC6A3SLC6A2NPSR1 | |
| SCHEMBL8038378 | 0.71 | MAOB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | disclosed |