Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL9580578 | 0.88 | MEN1 (0.36) | MEN1KMT2ATSHREGFRNPC1 | |
| Hydrochloric Acid SCHEMBL28924433 | 0.80 | TSHR (0.56) | MEN1KMT2ATSHRNPC1DNM1 | |
| Styrene SCHEMBL9580582 | 0.79 | EGFR (0.37) | MEN1KMT2AEGFRDNM1MLNR | |
| SCHEMBL9580631 | 0.79 | MEN1 (0.45) | MEN1KMT2ANPC1ADORA3ALDH1A1 | |
| SCHEMBL11081808 | 0.77 | DNM1 (0.54) | MEN1KMT2AEGFRDNM1MLNR | |
| SCHEMBL9580589 | 0.77 | DNM1 (0.40) | MEN1KMT2ADNM1MLNRNR1I2 | |
| Hydrochloric Acid SCHEMBL32674559 | 0.76 | KMT2A (0.55) | MEN1KMT2AEGFRDNM1MLNR | |
| Hydrochloric Acid SCHEMBL8070951 | 0.76 | KMT2A (0.55) | MEN1KMT2AEGFRDNM1MLNR | |
| SCHEMBL28921993 | 0.76 | MAPT (0.49) | MEN1KMT2ATSHRALDH1A1LMNA | |
| Styrene SCHEMBL26633379 | 0.76 | TSHR (0.58) | TSHRNPC1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | claimed |
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |