Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL9580578 | 0.88 | MEN1 (0.36) | EGFRDNM1MEN1KMT2AMAPK1 | |
| SCHEMBL11081808 | 0.80 | DNM1 (0.54) | EGFRDNM1MEN1KMT2AMAPK1 | |
| SCHEMBL9580596 | 0.79 | MEN1 (0.37) | EGFRDNM1MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL8070951 | 0.78 | KMT2A (0.55) | EGFRDNM1MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL32674559 | 0.78 | KMT2A (0.55) | EGFRDNM1MEN1KMT2AMAPK1 | |
| SCHEMBL9580589 | 0.75 | DNM1 (0.40) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Styrene SCHEMBL27863897 | 0.73 | KMT2A (0.53) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Styrene SCHEMBL27863894 | 0.73 | KMT2A (0.53) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Styrene SCHEMBL27460077 | 0.73 | TDP1 (0.50) | EGFRHTTTDP1LMNAALDH1A1 | |
| Styrene SCHEMBL28800480 | 0.72 | TSHR (0.47) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | claimed |
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |