Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444610 | 0.83 | CYSLTR2 (0.39) | MEN1KMT2ATP53CYSLTR2CYSLTR1 | |
| SCHEMBL11081808 | 0.81 | DNM1 (0.54) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL32674559 | 0.80 | KMT2A (0.55) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL8070951 | 0.80 | KMT2A (0.55) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL6633876 | 0.79 | TNNC1 (0.53) | MEN1KMT2ATP53CYSLTR2CYSLTR1 | |
| Styrene SCHEMBL701625 | 0.79 | THRB (0.51) | MEN1KMT2ATP53THRATHRB | |
| SCHEMBL9580596 | 0.77 | MEN1 (0.37) | DNM1MEN1KMT2ATP53MAPK1 | |
| Styrene SCHEMBL27863897 | 0.75 | KMT2A (0.53) | DNM1MEN1KMT2ATP53MAPK1 | |
| Styrene SCHEMBL27863894 | 0.75 | KMT2A (0.53) | DNM1MEN1KMT2ATP53MAPK1 | |
| Styrene SCHEMBL9580582 | 0.75 | EGFR (0.37) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | claimed |
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |