Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.83 |
| ▸ | MPEG1 | Q2M385 | 10/20 | 0.83 |
| ▸ | XIAP | P98170 | 6/20 | 0.83 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | PTGES | O14684 | 1/20 | 0.83 |
| ▸ | USP2 | O75604 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rapanone SCHEMBL2311835 | 0.91 | ALOX5 (1.00) | ALOX5MPEG1XIAPGPR84KDM4E | |
| Embelin SCHEMBL148744 | 0.91 | ALOX5 (1.00) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL12757276 | 0.91 | ALOX5 (1.00) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL6410428 | 0.89 | ALOX5 (0.97) | ALOX5MPEG1XIAPGPR84KDM4E | |
| Embelin SCHEMBL4653231 | 0.85 | ALOX5 (0.88) | ALOX5MPEG1XIAPGPR84KDM4E | |
| Embelin SCHEMBL21905447 | 0.82 | ALOX5 (0.81) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL12830675 | 0.82 | ALOX5 (0.74) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL9175113 | 0.77 | XIAP (1.00) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL9578683 | 0.76 | ALOX5 (0.88) | ALOX5MPEG1 | |
| SCHEMBL12757274 | 0.76 | XIAP (1.00) | ALOX5MPEG1XIAPGPR84KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220042-A | Antiasthmatics, antiallergens, cardiovasculsr disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0151995-B1 | NOVEL 1,4-BENZOQUINONE DERIVATIVES AND BENZENE DERIVATIVES, AND PROCESS FOR PREPARING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0151995-A2 | Novel 1,4-benzoquinone derivatives and benzene derivatives, and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-08-21 | — | — | EP | disclosed |