Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140352 | 0.77 | LMNA (0.42) | TRPM8LMNAALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL23795439 | 0.72 | LMNA (0.49) | TRPM8LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL5462561 | 0.72 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL17494477 | 0.69 | LMNA (0.35) | TRPM8LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17494476 | 0.69 | LMNA (0.35) | TRPM8LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28133297 | 0.68 | LMNA (0.68) | TRPM8LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL31138348 | 0.67 | LMNA (0.47) | TRPM8LMNAALDH1A1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL4997661 | 0.67 | SLC6A4 (0.41) | LMNASIGMAR1 | |
| SCHEMBL24138156 | 0.67 | LMNA (0.47) | TRPM8LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL28661661 | 0.64 | ESR1 (0.33) | HTR2AHTR2CHTR2BATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |