Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795439 | 0.95 | LMNA (0.49) | LMNACHRM2CHRM3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4997661 | 0.87 | SLC6A4 (0.41) | LMNAMEN1KMT2ASIGMAR1 | |
| SCHEMBL4408586 | 0.80 | CHRM3 (0.47) | LMNACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL28133297 | 0.78 | LMNA (0.68) | LMNACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL27131756 | 0.78 | OPRM1 (0.50) | LMNACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL24138156 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL31138348 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9580681 | 0.77 | TRPM8 (0.37) | LMNACHRM2CHRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28891615 | 0.76 | MEN1 (0.54) | LMNACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL3637483 | 0.76 | PKM (0.40) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034717-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | SANIONA A/S (DK) | 2024-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240034717-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | KCNN2, KCNJ2, KCNN1 | LMNA 1304/4885CHRM2 1458/4885CHRM3 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.