Diphenylether

Diphenylether

SCHEMBL9580853

CCO[Si](CC)(OCC)OCC.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.55
TSHR P16473 1/20 0.50
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
CRHBP P24387 1/20 0.41
RAB9A P51151 1/20 0.41
CRHR2 Q13324 1/20 0.41
NR1H2 P55055 1/20 0.40
BAX Q07812 1/20 0.40
MAOA P21397 1/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
PLA2G2A P14555 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL27835022 0.86 CA4 (0.56) LTA4HNPC1RAB9ALMNASMN1; SMN2
Diphenylether SCHEMBL9580825 0.84 LTA4H (0.52) LTA4HTSHRNPC1HPGDCRHBP
Diphenylether SCHEMBL9580920 0.84 LTA4H (0.53) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL19816431 0.83 LTA4H (0.41) LTA4HTSHRNPC1HPGDRAB9A
SCHEMBL31187708 0.83 LTA4H (0.41) LTA4HTSHRNPC1HPGDRAB9A
Diphenylether SCHEMBL9580840 0.81 LTA4H (0.52) LTA4HTSHRNPC1HPGDCRHBP
Biphenyl SCHEMBL21835012 0.81 ALDH1A1 (0.39) NPC1HPGDRAB9ALMNASMN1; SMN2
Anthracene SCHEMBL29043790 0.81 CYP2A6 (0.39) LTA4HNPC1HPGDRAB9ALMNA
Toluene SCHEMBL27989633 0.81 TSHR (0.48) LTA4HTSHRNPC1HPGDRAB9A
Aniline SCHEMBL2114370 0.79 TSHR (0.46) TSHRNPC1RAB9AMAOALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed