Diphenylether

Diphenylether

SCHEMBL9580920

CCCO[Si](CC)(OCCC)OCCC.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 10/20 0.53
TSHR P16473 1/20 0.46
PLA2G2A P14555 1/20 0.40
PPARA Q07869 1/20 0.38
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL9580937 0.87 LTA4H (0.52) LTA4HTSHRPLA2G2APPARANR1H2
Diphenylether SCHEMBL9580853 0.84 LTA4H (0.55) LTA4HTSHRPLA2G2ANR1H2BAX
Diphenylether SCHEMBL9580840 0.78 LTA4H (0.52) LTA4HTSHRPLA2G2ANR1H2BAX
Diphenylether SCHEMBL23093711 0.76 LTA4H (0.71) LTA4HTSHRPLA2G2ANR1H2BAX
SCHEMBL105329 0.76
SCHEMBL27845338 0.74 LTA4H (0.84) LTA4HTSHRPLA2G2APPARA
Diphenylether SCHEMBL296590 0.73 LTA4H (0.75) LTA4HTSHRPLA2G2ANR1H2BAX
Water SCHEMBL27808036 0.73
Ammonia Solution, Strong SCHEMBL28547617 0.73
Diphenylether SCHEMBL9580825 0.73 LTA4H (0.52) LTA4HTSHRPLA2G2ANR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed