Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL3007716 | 0.87 | ALDH1A1 (0.52) | PAMGLATDP1ALDH1A1TSHR | |
| Styrene SCHEMBL3446819 | 0.87 | ALDH1A1 (0.52) | PAMGLATDP1ALDH1A1TSHR | |
| Styrene SCHEMBL27543907 | 0.87 | ALDH1A1 (0.52) | PAMGLATDP1ALDH1A1TSHR | |
| Styrene SCHEMBL11069911 | 0.84 | ALDH1A1 (0.48) | PAMGLATDP1ALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL9580642 | 0.83 | MEN1 (0.46) | PAMALDH1A1LMNAMAPTKDM4E | |
| Styrene SCHEMBL28058911 | 0.82 | ALDH1A1 (0.47) | GLATDP1ALDH1A1TSHRCYP3A4 | |
| Styrene SCHEMBL27854771 | 0.82 | ALDH1A1 (0.54) | PAMALDH1A1TSHRMAOBMAPT | |
| Styrene SCHEMBL1507248 | 0.82 | ALDH1A1 (0.58) | PAMTDP1ALDH1A1TSHRMAOB | |
| Styrene SCHEMBL28105447 | 0.81 | ALDH1A1 (0.45) | GLATDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL7177819 | 0.80 | PAM (0.47) | PAMGLATDP1MAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |