Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580631 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Styrene SCHEMBL9580863 | 0.83 | PAM (0.41) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14735705 | 0.82 | PAM (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7199351 | 0.81 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Methacrylic Acid SCHEMBL20574356 | 0.79 | CACNA1B (0.48) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28613779 | 0.78 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Cinnamic Acid SCHEMBL27813787 | 0.78 | HDAC3 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Styrene SCHEMBL28267358 | 0.78 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Methacrylic Acid SCHEMBL390857 | 0.77 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Methacrylic Acid SCHEMBL2545778 | 0.77 | THRB (0.52) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |