Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.34 |
| ▸ | GABRP | O00591 | 5/20 | 0.34 |
| ▸ | GABRD | O14764 | 5/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.34 |
| ▸ | GABRE | P78334 | 5/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684115 | 0.85 | GAA (0.36) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9582428 | 0.84 | GAA (0.40) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9683955 | 0.84 | GAA (0.38) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9683202 | 0.81 | GABRP (0.37) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9685317 | 0.80 | GAA (0.38) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9684131 | 0.79 | GAA (0.37) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9581337 | 0.79 | GAA (0.38) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9684814 | 0.77 | GAA (0.37) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9582286 | 0.75 | GABRA2 (0.38) | GAADDR1GABRB3GABRA2GABRB2 | |
| SCHEMBL9730755 | 0.73 | GAA (0.43) | GAAGABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155863-A | — | — | None | — | — | JP | disclosed |
| JP-H05155863-A | PHENYL-SUBSTITUTED HETEROCYCLIC COMPOUND, ITS PREPARATION, INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING THE COMPOUND | IMPERIAL CHEM IND PLC <ICI> | 1993-06-22 | — | — | JP | disclosed |
| EP-0481604-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-22 | — | — | EP | disclosed |