Diphenylether

Diphenylether

SCHEMBL9580937

CCCO[Si](CCC)(OCCC)OCCC.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 10/20 0.52
TSHR P16473 1/20 0.44
MAPT P10636 2/20 0.40
ALOX12 P18054 1/20 0.40
PLA2G2A P14555 1/20 0.39
HTT P42858 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PPARA Q07869 1/20 0.37
LMNA P02545 1/20 0.37
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL9580920 0.87 LTA4H (0.53) LTA4HTSHRMAPTALOX12PLA2G2A
Diphenylether SCHEMBL9580825 0.87 LTA4H (0.52) LTA4HTSHRMAPTALOX12PLA2G2A
Diphenylether SCHEMBL9580898 0.81 LTA4H (0.54) LTA4HTSHRMAPTALOX12PLA2G2A
SCHEMBL107663 0.77
SCHEMBL106648 0.76 RAB9A (0.40) MAPTALOX12ALDH1A1KMT2A
Diphenylether SCHEMBL23093711 0.75 LTA4H (0.71) LTA4HTSHRMAPTALOX12PLA2G2A
Ammonia Solution, Strong SCHEMBL820690 0.75
SCHEMBL6356238 0.74 LTA4H (0.39) LTA4HKMT2ALMNA
SCHEMBL423709 0.74 LTA4H (0.41) LTA4HTSHRMAPTALOX12
SCHEMBL20658031 0.73 IDO1 (0.44) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed