Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740134 | 0.73 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11733305 | 0.68 | L3MBTL1 (0.63) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11736823 | 0.67 | TYMP (0.60) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL855321 | 0.64 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL17271400 | 0.63 | L3MBTL1 (0.56) | L3MBTL1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL7553005 | 0.62 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL212224 | 0.62 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL20828261 | 0.60 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2TYMP | |
| SCHEMBL7213442 | 0.59 | HSD17B10 (0.50) | L3MBTL1KDM4EALDH1A1GAARXFP1 | |
| SCHEMBL20828259 | 0.59 | POLB (0.64) | L3MBTL1KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553119-A1 | HETEROCYCLIC COMPOUNDS | ZENECA LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5187176-A | 1-PHENYL SUBSTITUTED PYRIMIDONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| WO-1992006964-A1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |