Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 10/20 | 0.40 |
| ▸ | METAP2 | P50579 | 7/20 | 0.40 |
| ▸ | METAP1 | P53582 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460724 | 0.96 | STAT3 (0.59) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3522520 | 0.89 | STAT3 (0.47) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6009229 | 0.87 | STAT3 (0.45) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29822398 | 0.83 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL432185 | 0.83 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| Acetoacetic Acid SCHEMBL9748613 | 0.82 | STAT3 (0.48) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9582382 | 0.82 | NPC1 (0.44) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL599851 | 0.82 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL9418754 | 0.82 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL29560659 | 0.82 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236914-A | Antitumor agents, viricides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-08-17 | — | — | US | disclosed |