Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | CYCS | P99999 | 4/20 | 0.35 |
| ▸ | CBFB | Q13951 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582368 | 0.82 | STAT3 (0.57) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| SCHEMBL460724 | 0.81 | STAT3 (0.59) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| Acetoacetic Acid SCHEMBL9752522 | 0.78 | MEN1 (0.50) | KDM4EHPGDSMN1; SMN2TOP1CYCS | |
| SCHEMBL3522520 | 0.78 | STAT3 (0.47) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3518268 | 0.75 | STAT3 (0.43) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| SCHEMBL6009229 | 0.73 | STAT3 (0.45) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| SCHEMBL29822398 | 0.73 | KDM4E (0.46) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL432185 | 0.73 | KDM4E (0.46) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL28025879 | 0.73 | STAT3 (0.49) | STAT3STAT1KDM4ENPC1RAB9A | |
| SCHEMBL31550992 | 0.73 | STAT3 (0.86) | STAT3STAT1TOP1CYCSABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510074-A1 | PORPHYRIN DERIVATIVES AND METALLOPORPHYRINS OPTIONALLY COUPLED WITH A BIOLOGICALLY ACTIVE MOLECULE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CIS BIO INTERNATIONAL (FR) | 1992-10-28 | — | — | EP | disclosed |