Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 10/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | METAP2 | P50579 | 4/20 | 0.35 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582368 | 0.89 | STAT3 (0.57) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3518268 | 0.89 | STAT3 (0.43) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6009229 | 0.86 | STAT3 (0.45) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL460724 | 0.86 | STAT3 (0.59) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3520923 | 0.82 | STAT3 (0.42) | STAT3STAT1TERT | |
| SCHEMBL3522525 | 0.81 | CBFB (0.40) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL144247 | 0.80 | STAT3 (0.47) | STAT3STAT1 | |
| Acetoacetic Acid SCHEMBL9748613 | 0.78 | STAT3 (0.48) | STAT3STAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL432185 | 0.75 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL29822398 | 0.75 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024215973-A1 | METALLOPORPHYRINS FOR REDUCING ISCHAEMIA-REPERFUSION INJURIES | BIOMIMETIX JV, LLC (US) | 2024-10-17 | — | — | WO | disclosed |
| EP-1718201-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20150344509-A1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2015-12-03 | — | — | US | disclosed |
| US-9096628-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140080797-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8618089-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120264725-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES (US) | 2012-10-18 | — | — | US | disclosed |
| US-8183364-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES | 2010-12-02 | — | — | US | disclosed |
| US-7807825-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080021007-A1 | Substituted Porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344509-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885NPC1 2572/4885 |
| US-20120264725-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885NPC1 2572/4885 |
| US-20080021007-A1 | Substituted Porphyrins | SOD3, SOD1, PRDX3 | STAT3 4525/4885STAT1 4424/4885NPC1 2056/4885 |
| US-20140080797-A1 | SUBSTITUTED PORPHYRINS | PPOX, FECH, MB | STAT3 546/4885STAT1 729/4885NPC1 2572/4885 |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | SOD3, SOD1, PRDX3 | STAT3 4527/4885STAT1 4415/4885NPC1 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.