Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 9/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582818 | 1.00 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL8091043 | 1.00 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL11002928 | 0.88 | LMNA (0.56) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL8083425 | 0.88 | LMNA (0.70) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL9033931 | 0.84 | LMNA (0.43) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL9032049 | 0.84 | LMNA (0.45) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10996910 | 0.84 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL11000457 | 0.83 | LMNA (0.67) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10432848 | 0.83 | LMNA (0.51) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL9581753 | 0.82 | KDM4E (0.71) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185337-A | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |