Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809454 | 0.82 | MEN1 (0.46) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL5501580 | 0.81 | CHRNA7 (0.44) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL5500525 | 0.81 | CHRNA7 (0.44) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL27623429 | 0.81 | CHRNA7 (0.44) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4811022 | 0.80 | HTR3E (0.43) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4815140 | 0.79 | TSHR (0.41) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4816473 | 0.79 | TSHR (0.41) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4811857 | 0.79 | TRPM8 (0.43) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4804786 | 0.78 | LMNA (0.41) | TSHRMEN1KMT2AGAAHTR3E | |
| SCHEMBL4811547 | 0.77 | TSHR (0.40) | TSHRMEN1KMT2AGAAHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262385-A | Pyrimidine ring containing | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0468766-A1 | Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor | Mitsubishi Chemical Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |