Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399447 | 0.86 | RARB (0.47) | RARBRARARARGFAAHTHRB | |
| SCHEMBL29009858 | 0.80 | KMT2A (0.43) | FAAHALOX15HPGD | |
| SCHEMBL9399210 | 0.78 | ALOX15 (0.52) | RARBRARARARGFAAHTHRB | |
| SCHEMBL28805567 | 0.72 | THRB (0.64) | RARBRARAFAAHTHRBTHRA | |
| SCHEMBL10181075 | 0.71 | ALOX15 (0.41) | ALOX15ALDH1A1 | |
| SCHEMBL29368642 | 0.70 | KDM4E (0.44) | THRBALOX15KAT8 | |
| SCHEMBL1992822 | 0.70 | KMT2A (0.44) | ALOX15ALDH1A1 | |
| SCHEMBL1998098 | 0.70 | KMT2A (0.44) | ALOX15HPGD | |
| SCHEMBL15548000 | 0.70 | ALOX15 (0.70) | ALOX15 | |
| SCHEMBL24372243 | 0.69 | THRB (0.64) | RARBRARAFAAHTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |