SCHEMBL9584136

SCHEMBL9584136

C1CN2CC1C(c1nn[nH]n1)C2

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.40
CHRM1 P11229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9584654 0.68 CHRM2 (0.39) CHRM2CHRM1
SCHEMBL7922060 0.68 CHRM2 (0.42) CHRM2
SCHEMBL10433651 0.65 CHRM2 (0.39) CHRM2
SCHEMBL9293370 0.64 CHRM2 (0.38) CHRM2CHRM1
SCHEMBL9486003 0.63 CHRM2 (0.38) CHRM2
SCHEMBL9052091 0.62 CHRNA7 (0.43) CHRM2CHRM1
SCHEMBL10433641 0.62 CHRM2 (0.43) CHRM2
SCHEMBL9489609 0.61 CHRM2 (0.36) CHRM2CHRM1
SCHEMBL13804315 0.61 LTA4H (0.43)
SCHEMBL12259816 0.61 HSD11B1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0402056-A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them Beecham Group p.l.c. (GB) 1990-12-12 EP claimed
US-5217975-A AZABICYCLIC COMPOUNDS FOR TREATING DEMENTIA BEECHAM GROUP P.L.C. (GB) 1993-06-08 US disclosed
EP-0402056-A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them Beecham Group p.l.c. (GB) 1990-12-12 EP disclosed