SCHEMBL95847

SCHEMBL95847

Nc1cc2ccccc2c(S(=O)(=O)O)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.51
TTR P02766 1/20 0.44
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
CASP6 P55212 1/20 0.41
SUMO2 P61956 4/20 0.41
SUMO1 P63165 4/20 0.41
SENP7 Q9BQF6 4/20 0.41
SENP2 Q9HC62 4/20 0.41
SENP1 Q9P0U3 4/20 0.41
SENP3 Q9H4L4 3/20 0.39
HPGD P15428 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
APP P05067 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601499 0.87 CYP2D6 (0.53) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL5033007 0.86 CYP2D6 (0.64) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL6454177 0.86 CYP2D6 (0.51) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL22191870 0.86 CYP2D6 (0.47) CYP2D6TTRALDH1A1HSD17B10CYP2C19
Potassium SCHEMBL9695842 0.84 CYP2D6 (0.50) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL1126146 0.84 CYP2D6 (0.54) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL9695827 0.84 CYP2D6 (0.50) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL3792681 0.83 CYP2D6 (0.49) CYP2D6TTRALDH1A1HSD17B10CYP2C19
SCHEMBL9326730 0.82 HPRT1 (0.39) CYP2D6TTRALDH1A1HSD17B10HPGD
SCHEMBL547342 0.81 CYP2D6 (0.54) CYP2D6TTRALDH1A1HSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8816095-B2 Na channels, disease, and related assays and compositions GEORGETOWN UNIVERSITY (US) 2014-08-26 US claimed
US-20140024137-A1 METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS NUBAD LLC 2014-01-23 US claimed
US-20130344588-A1 DEVICES AND METHODS FOR CONCENTRATION AND ANALYSIS OF FLUIDS MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) 2013-12-26 US claimed
EP-2330908-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER Georgetown University (US) 2011-06-15 EP claimed
WO-2010019967-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER GEORGETOWN UNIVERSITY (US) 2010-02-18 WO claimed
EP-0116884-B1 NITRO-NAPHTHYLAMINE SULPHONIC ACIDS BAYER AG (DE) 1986-04-09 EP claimed
US-20250361270-A1 TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2025-11-27 US disclosed
EP-4025125-B1 BREATH ANALYZER HETERON BIOTECHNOLOGIES LLC (US) 2025-08-06 EP disclosed
US-12195558-B2 Targeted delivery system and methods of use therefor Sanford Burnham Prebys Medical Discovery Institute (US) 2025-01-14 US disclosed
US-20240150397-A1 TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR Sanford Burnham Prebys Medical Discovery Institute 2024-05-09 US disclosed
US-20230381329-A1 Zwitterion Polymer-Drug Conjugates UNIV UTAH RES FOUND (US) 2023-11-30 US disclosed
US-11801307-B2 Antibody-polymer-drug conjugates UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-10-31 US disclosed
CN-107083444-B Monochromatic multiplex quantitative PCR 犹他大学研究基金会 2023-03-14 CN disclosed
WO-1999052708-A1 LIQUID LABELING WITH FLUORESCENT MICROPARTICLES LUMINEX CORPORATION (US) 1999-10-21 WO disclosed
WO-1999037814-A9 MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS LUMINEX CORP (US) 1999-10-14 WO disclosed
WO-1999037814-A1 MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS LUMINEX CORPORATION (US) 1999-07-29 WO disclosed
WO-1999019515-A1 PRECISION FLUORESCENTLY DYED PARTICLES AND METHODS OF MAKING AND USING SAME LUMINEX CORPORATION (US) 1999-04-22 WO disclosed
US-5583051-A Use of a fiber optic probe for organic species determination THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY (US) 1996-12-10 US disclosed
WO-1995030919-A1 ILLUMINATOR ELEMENTS FOR CONVENTIONAL LIGHT MICROSCOPES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-11-16 WO disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801307-B2 Antibody-polymer-drug conjugates FCGR1A, FCGR2A, CD79B CYP2D6 2146/4885TTR 1068/4885ALDH1A1 2091/4885
US-20230381329-A1 Zwitterion Polymer-Drug Conjugates ZW10, NUP205, DNPEP CYP2D6 4699/4885TTR 208/4885ALDH1A1 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.