Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95847 | 0.82 | CYP2D6 (0.51) | KDM4ECYP2D6ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL2343292 | 0.81 | L3MBTL1 (0.45) | HPRT1KDM4ECYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL10904716 | 0.78 | HPRT1 (0.46) | HPRT1HTR6ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL251761 | 0.74 | CYP2D6 (0.39) | HPRT1KDM4ECYP2D6HTR6ALDH1A1 | |
| SCHEMBL601499 | 0.73 | CYP2D6 (0.53) | HPRT1KDM4ECYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL677653 | 0.72 | ALDH1A1 (0.48) | HPRT1POLBKDM4EHTTRAD52 | |
| SCHEMBL29463710 | 0.72 | ALDH1A1 (0.48) | HPRT1POLBKDM4EHTTRAD52 | |
| SCHEMBL31281983 | 0.72 | ALDH1A1 (0.48) | HPRT1POLBKDM4EHTTRAD52 | |
| SCHEMBL17685470 | 0.71 | NR1I2 (0.39) | HPRT1POLBKDM4EHTTRAD52 | |
| SCHEMBL10744779 | 0.71 | CYP1A2 (0.41) | KDM4EHTTCYP2D6ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329682-B1 | A METHOD FOR ASCERTAINING THE HISTORY OF A CONDITION OF THE BODY FROM A SINGLE BLOOD SAMPLE | SAUNDERS ALEXANDER M (US) | 1994-03-09 | — | — | EP | disclosed |