SCHEMBL9586137

SCHEMBL9586137

COC1(c2ccc(O)c(CO)c2)CCOCC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 13/20 0.43
KLF10 Q13118 1/20 0.37
PKM P14618 1/20 0.36
OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9216511 0.79 ALDH1A1 (0.47) ALOX5PKM
SCHEMBL8630364 0.77 ALOX5 (0.42) ALOX5
SCHEMBL9585927 0.76 ERN1 (0.45) ALOX5
SCHEMBL6026181 0.75 ALOX5 (0.60) ALOX5
SCHEMBL8698139 0.75 ALOX5 (0.51) ALOX5
SCHEMBL1599480 0.73 ALOX5 (0.54) ALOX5
SCHEMBL9229297 0.72 ALOX5 (0.45) ALOX5
SCHEMBL9100023 0.71 ALOX5 (0.45) ALOX5
SCHEMBL29125384 0.69 ALOX5 (0.40) ALOX5
SCHEMBL30594923 0.69 ALOX5 (0.40) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232930-A Antiinflammatory antiallergen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-08-03 US disclosed
EP-0500205-A1 Benzodioxole derivatives ZENECA LIMITED (GB) 1992-08-26 EP disclosed