SCHEMBL9586348

SCHEMBL9586348

CCOC(=O)N1CCOC1=O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 6/20 0.51
TSHR P16473 1/20 0.47
ALDH1A1 P00352 2/20 0.44
RECQL P46063 1/20 0.43
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.42
FAAH O00519 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15667494 0.81 NAAA (0.45) NAAATSHRALDH1A1RECQLMAPT
SCHEMBL3362031 0.80 NAAA (0.46) NAAAMAPTFAAH
SCHEMBL14433154 0.80 ALDH1A1 (0.50) NAAATSHRALDH1A1MAPT
SCHEMBL25439031 0.80 NAAA (0.39) NAAAFAAH
SCHEMBL4195675 0.79 NAAA (0.40) NAAAFAAH
SCHEMBL675612 0.76 NAAA (0.64) NAAAFAAH
SCHEMBL17420841 0.76 TSHR (0.65) TSHRALDH1A1RECQLMAPTHTT
SCHEMBL1563999 0.76 USP2 (0.49) NAAARECQL
SCHEMBL2824281 0.75 MAPK1 (0.46) NAAATSHRALDH1A1HTT
SCHEMBL11681599 0.75 NAAA (0.60) NAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5245032-A CATALYTIC PROCESSES FOR THE PREPARATION OF N,N,N-TRISUBSTITUTED NITROGEN-CONTAINING COMPOUNDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-09-14 US claimed
EP-0476782-A1 Catalytic processes for the preparation of N,N,N-trisubstituted nitrogen-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP claimed
US-5245032-A CATALYTIC PROCESSES FOR THE PREPARATION OF N,N,N-TRISUBSTITUTED NITROGEN-CONTAINING COMPOUNDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-09-14 US disclosed
EP-0476782-A1 Catalytic processes for the preparation of N,N,N-trisubstituted nitrogen-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed
US-4416818-A Preparation of N-alkoxycarbonyl-substituted cyclic lactams and ketones THE DOW CHEMICAL COMPANY (US) 1983-11-22 US disclosed
US-4381401-A Aminoethylation process THE DOW CHEMICAL COMPANY (US) 1983-04-26 US disclosed